Fig. 8.
Three-dimensional reconstruction of the atrioventricular junction (AVJ) conduction system. A—C: Endocardial view of the conduction system of each normal heart. Left side of each panel displays the connective tissue and blood vessels surrounding the conduction system, as well as the location of the conduction system within the triangle of Koch of each preparation. Right side of each panel shows the conduction system and the three planes where Cx43 was quantified. D: Conduction system reconstruction of the heart with dilated cardiomyopathy. Left side of panel displays the same endocardial view as shown in A—C. Middle of panel shows the conduction system rotated 90 degrees to more clearly show leftward extension. CFB, central fibrous body; IAS, interatrial septum; TT, tendon of Todaro; VS, ventricular septum; A—P, S—I, D—V, anterior—posterior, superior—inferior, and dorsal—ventral orientations.