(a–d) Neurological motor function 48h-3 weeks post-injury assessed by the composite neuroscore (boxplots showing medians, interquartile range and min-max values; maximum achievable score 12) among sham-injured wild-type controls and brain-injured, age-matched wild-type littermates (WT), Nogo-A/B+/− and Nogo-A/B−/− mice. When compared to sham-injured animals, brain-injured WT animals had significantly lower neuroscores up to 2 weeks post-injury (a–c; *p<0.05). At 3 weeks post-injury, brain-injured Nogo-A/B−/− animals had significantly lower neuroscores when compared to brain-injured, WT controls (d; #p<0.05).