Figure 4. Reduced chondrogenic proliferation and increased bone remodeling in mouse with induced Wnt signaling.
The healing tissue was scraped from WT and sFRP1−/− mice, total RNA was isolated, and analyzed for chondrogenic markers and bone remodeling markers. Relative transcript levels are presented ± SEM as error bars, WT as open box (□) and sFRP1−/− as filled box (■). * represents p-value < 0.01.