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. Author manuscript; available in PMC: 2009 Oct 5.
Published in final edited form as: Science. 2005 May 12;308(5729):1794–1798. doi: 10.1126/science.1110324

Fig. 1.

Fig. 1

Dissection of human embryonic brain tissues and generation of human SAGE libraries. (A) A top view of a 14-week human embryonic brain. Tissues were dissected from perisylvian regions in the left (L) and right (R) hemispheres. (B) A side view of a 14-week human embryonic right hemisphere. Tissues in the frontal (f) (red) and occipital (o) (blue) ventricular regions containing dividing cells were dissected. The dorsal cortex (d) is on the top. (C) The left side view of a real 14-week human embryonic brain. The perisylvian region is circled. (D) Summary of human brain SAGE libraries. The male (M) and female (F) brains are listed. At least 55,000 tags were sequenced in each library. (E) Summary of differentially expressed genes detected by SAGE analysis between the left-right hemispheres. Numbers of genes that are highly expressed in the left (L>R) or right (L<R) are listed with confidence levels p>99% and 95%<p<99%.