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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Semin Cell Dev Biol. 2009 Feb 13;20(3):321–329. doi: 10.1016/j.semcdb.2009.02.002

Figure 1.

Figure 1

Mitochondrial influence on signal transduction in a metazoan cell. An idealized representation of redox-regulated information flow (red arrows) mediating the production of a transcriptional response to a signal (in this case, binding of an extracellular ligand to its transmembrane receptor). Note that signals impinging on gene expression might also originate intracellularly along these pathways.