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Generation of angiotensin II by serum chymase. The graph shows results of measurement of angiotensin II-generating capacity of native serum and of the same sample spiked with recombinant human chymase (50 or 100 pM). Samples were pre-incubated with an ACE inhibitor (captopril), a chymase inhibitor (chymostatin), or with both inhibitors, as indicated.
