Skip to main content
. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Eur J Pharmacol. 2009 May 20;615(1-3):66–75. doi: 10.1016/j.ejphar.2009.05.008

Fig. 3. 5-HT efflux in the hypothalamus and cortex.

Fig. 3

Rats were pretreated with clorgyline (CLG; 2 mg/kg, i.p.) 12 h before dual-probe microdialysis. Data for changes in 5-HT efflux in the hypothalamus (panel A) and cortex (panel B) were obtained from the same animals. 5-HTP (mg/kg; 5, 10, 15, 20 and 25) was intraperitoneally administered at time zero, as indicated by the solid arrows. Data are expressed as mean (fold increase above baseline, sample size n = 5–6 rats) ± S.E.M. Asterisks (*) indicating significance (P< 0.05) are omitted from the graphs for the sake of clarity.