. Author manuscript; available in PMC: 2009 Oct 5.

Published in final edited form as: Am J Physiol Renal Physiol. 2004 Mar 23;287(1):F81–F89. doi: 10.1152/ajprenal.00349.2003

Table 2.

Functional indexes of PAN-treated and sham rats

	BW₁, g	BW₂, g	LKW, g	BUN, mg/dl	P_Cr, mg/dl	C_cr, ml · min⁻¹ · kg BW⁻¹	BP, mmHg	P_NOx, μM	P_NOx/P_Cr
SD Sham	402±9	478±11	1.6±0.1	24±2	0.28±0.02	9.9±0.8	95±3	9±1	0.37±0.07
SD PAN	386±6	362±29^*	2.7±0.2^*	199±70^*	4.43±1.50^*	0.9±0.1^*	86±6	34±12	0.09±0.01^*
WF Sham	282±9^†	331±11^†	1.1±0.1^†	20±1	0.23±0.02	10.0±1.0	75±2^†	13±2	0.64±0.11
WF PAN	309±2^†	356±5	1.5±0.1^†	23±1^†	0.23±0.02^†	11.4±0.8^†	73±2^†	9±1^†	0.45±0.05^†

Values are means ± SE. BW₁, average body weight in control; BW₂, average BW after 15 wk; LKW, left kidney weight at death; BUN, blood urea nitrogen; P_Cr, plasma creatinine clearance; C_cr, creatinine clearance; BP, blood pressure; P_NOx, plasma NO₂ + NO₃; SD, Sprague-Dawley rat; WF, Wistar-Furth rat; PAN, puromycin aminonucleoside.

P < 0.05, Sham vs. PAN.

^†

P < 0.01, SD vs. WF.