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RLGS analysis for tumor-associated DNA hypermethylation. (a) Representative RLGS loci for non-malignant TCL1-tg mouse spleen (NL) and specified TCL1-tg splenic B-cell tumors. Arrows indicate specific RLGS loci (4D57, 3C24 and 2C33) lost/hypermethylated in one or more of the tumors. (b) Frequency of altered RLGS loci for each tumor is indicated.
