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. 2009 Aug 10;29(20):5578–5589. doi: 10.1128/MCB.00283-09

FIG. 8.

FIG. 8.

SLP-76 relocalization correlates with support of integrin function. (A) Adhesion to ICAM-1 among naïve CD4-Cre SLP-76 cHET, cKO, cKO:RK SLP-76, or ADAP−/− T cells was measured in response to the indicated stimuli. Adhesion levels ranged from 5 to 10% in unstimulated (unstim) cells to 80% at maximum. Data represent means ± standard deviations normalized to unstimulated cHET cell results from four experiments. Asterisks indicate a statistical significance of P < 0.05. (B) Adhesion to ICAM-1 was measured among Ubc-CreT2 SLP-76 cKO T-cell blasts retrovirally reconstituted with vector only or with WT, G2, or SLP-76. Data represent means ± standard deviations normalized to unstimulated WT cell results from three experiments. ns, not significant.