TABLE 3.
ROC curve values for prediction of Streptococcus pneumoniae infection and bacteremia in patients with CAP
| ROC curve parametera | Marker of infection values
|
||
|---|---|---|---|
| BDL | WBC | CRP | |
| S. pneumoniae infection | |||
| AUC (95% CI) | 0.82 (0.68-0.92) | 0.79 (0.63-0.90) | 0.72 (0.56-0.85) |
| Optimal cutoff value | 125 | 13.3 | 187 |
| Sensitivity (%) | 65 | 82 | 65 |
| Specificity (%) | 100 | 62 | 77 |
| PPV (%) | 100 | 42 | 43 |
| NPV (%) | 90 | 91 | 87 |
| S. pneumoniae bacteremia | |||
| AUC (95% CI) | 0.86 (0.72-0.95) | 0.80 (0.65-0.91) | 0.81 (0.66-0.91) |
| Optimal cutoff value | 225 | 16.8 | 187 |
| Sensitivity (%) | 75 | 67 | 83 |
| Specificity (%) | 97 | 87 | 77 |
| PPV (%) | 69 | 35 | 23 |
| NPV (%) | 97 | 96 | 98 |
a
The units of measurement for the optimal cutoff values: BDL, CFU equivalents/ml; WBC, number of cells × 109/liter; CRP, mg/liter. 95% CI, 95% confidence interval.