TABLE 3.

Serological patterns and EBV diagnosis for the 20/32 serological patterns that occurred in <10 patients^a

Pattern no.b	“Presumed” EBV stage	BioPlex 2200 resultc					No. of patients
							In study	With EBV diagnosis based on medical record reviewd
		VCA IgG	EBNA-1 IgG	EA-D IgG	VCA IgM	Het IgM		EBV naive	Primary acute	Past infection	Recovery/ reactivation	Inconclusive
3	Primary acute	Pos	Neg	Neg	Pos	Neg	7	0	2	3	1	1
6	Primary acute	Pos	Neg	Neg	Neg	Pos	0	0	0	0	0	0
7	Primary acute	Pos	Neg	Pos	Pos	Neg	2	0	0	0	1	1
8	Primary acute	Pos	Neg	Neg	Pos	Pos	1	0	1	0	0	0
10	Primary acute	Pos	Neg	Pos	Neg	Pos	0	0	0	0	0	0
11	Primary acute	Pos	Neg	Pos	Pos	Pos	4	0	2	0	1	1
13	Past infection	Neg	Pos	Pos	Neg	Neg	6	3	1	0	0	2
16	Recov/Reacte	Neg	Pos	Neg	Pos	Neg	0	0	0	0	0	0
18	Recov/React	Neg	Pos	Pos	Pos	Neg	0	0	0	0	0	0
19	Recov/React	Neg	Pos	Neg	Pos	Pos	0	0	0	0	0	0
20	Recov/React	Pos	Pos	Neg	Neg	Pos	0	0	0	0	0	0
21	Recov/React	Neg	Pos	Pos	Neg	Pos	0	0	0	0	0	0
23	Recov/React	Pos	Pos	Neg	Pos	Pos	1	0	0	1	0	0
24	Recov/React	Neg	Pos	Pos	Pos	Pos	0	0	0	0	0	0
25	Recov/React	Pos	Pos	Pos	Neg	Pos	0	0	0	0	0	0
26	Recov/React	Pos	Pos	Pos	Pos	Pos	4	0	2	2	0	0
27	Unknown	Neg	Neg	Pos	Neg	Neg	7	4	1	1	1	0
28	Unknown	Neg	Neg	Neg	Neg	Pos	1	0	1	0	0	0
31	Unknown	Neg	Neg	Pos	Neg	Pos	3	0	2	0	0	1
32	Unknown	Neg	Pos	Neg	Neg	Pos	0	0	0	0	0	0
					Totals:		36	7	12	7	4	6

^aShown are the 20/32 possible serological patterns that occurred in <10 patients.

^bPattern numbers correspond to those shown in Table 1.

^cPos, positive; Neg, negative.

^dSee Materials and Methods for classification of EBV stage.

^eRecov/React, recovery/reactivation: those patients who are in a late acute infection stage or have benign reactivation.