Figure 7. Presence of NMMHC II-a within the protein homogenate from mitochondrial fractions.
Immunoblot analysis of protein homogenate from the whole cell extract (WCE) and mitochondrial fractions (MF) isolated from the cochlea and kidney demonstrates presence of 220 kDa NMHC-IIa. The mitochondrial fractions from the cochlea and kidney are positive for presence of the mitochondrial marker Cytochrome C (15 kDa) and negative for cytoplasmic marker GAPDH (37 kDa). The protein homogenate from the whole cell extracts (WCE) from which the mitochondria were fractionated is immuno-positive for NMHC-IIa, GAPDH and Cytochrome C.