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. Author manuscript; available in PMC: 2009 Oct 5.
Published in final edited form as: Ann Intern Med. 2008 Nov 4;149(9):601–611. doi: 10.7326/0003-4819-149-9-200811040-00003

APPENDIX FIGURE 5. Serum 24-h mean GH and IGF-I levels every 6 months over 2 years.

APPENDIX FIGURE 5

GH (Panel A) and IGF-I (Panel B) data were not normally distributed and were analyzed on the natural logarithmic scale; line graphs show geometric means and 95% confidence intervals. An asterisk indicates that the fold change from baseline to 24 months was significant for that group (Bonferroni-adjusted P<0.001). In Panel A, the 24-h mean GH for young men and women combined (~1.3 μg/L) is indicated by a dashed line. In Panel B the lower limit of the IGF-I normal range is indicated: older adults (59-225 μg/L, lower dotted line); young adults aged 21-25 (116-358 μg/L, upper dashed line). GH=growth hormone, IGF-I=insulin-like growth factor-I