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Penetrance tables for two disease loci under epistatic models
| a Epistatic model I | |||||
|---|---|---|---|---|---|
| Genotype at locus A | Genotype at locus B |
Marginal effect | |||
| b/b (1/4) | b/B (1/2) | BB (1/4) | |||
| a/a (1/4) | 0 | 0 | 1 | 0.25 | |
| a/A (1/2) | 0 | 1 | 0 | 0.5 | |
| AA (1/4) | 1 | 0 | 0 | 0.25 | |
| Marginal effect | 0.25 | 0.5 | 0.25 | ||
| b Epistatic model II | |||||
| a/a (1/4) | 0 | 0 | 1 | 0.25 | |
| a/A (1/2) | 0 | 0.5 | 0 | 0.25 | |
| AA (1/4) | 1 | 0 | 0 | 0.25 | |
| Marginal effect | 0.25 | 0.25 | 0.25 | ||
