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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2009 Sep 1;52(1):106–113. doi: 10.1097/QAI.0b013e3181a4f9c4

Table 1.

Antiretroviral Regimen Strategie

Regimen Suppressed
at 1yr		 Range Sources
Strategy A: Current WHO Guidelines
     Regimen 1: 2 NRTIs + NNRTI (based on AZT
     + 3TC + NVP or EFV)		 85 60–90 Boulle,39 Orrell,25
Calmy40
     Regimen 2: 2 NRTIs + PI/r (based on TDF +
     3TC + LPV/r)		 70 50–80 De mendoza41,
Kaufman42, Robbins43
Strategy B: Initial Triple NRTI Regimen
     Regimen 1: 3 NRTIs (based on AZT + 3TC +
     ABC)		 60 40–70 Staszewski44, DART14,
Srikantiah45
     Regimen 2: 2 NRTIs + NNRTI (based on TDF
     + 3TC + NVP or EFV)		 80 50–90 Gullick46
     Regimen 3: 2 NRTIs + PI/r (based on TDF +
     3TC + LPV/r)		 70 50–80 De mendoza41,
Kaufman42, Robbins43
Strategy C: 3rd Regimen with 2nd Generation PI
     Regimen 1: 2 NRTIs + NNRTI (based on AZT
     + 3TC + NVP or EFV)		 85 60–90 Boulle,39 Orrell,25
Calmy40
     Regimen 2: 2 NRTIs + PI/r (based on TDF +
     3TC + LPV/r)		 70 50–80 De mendoza41,
Kaufman42, Robbins43
     Regimen 3: 2 NRTIs + 2nd gen PI/r (based on
     TDF + 3TC + DNV/r)		 60 30–75 Madruga16

3TC - Lamivudine NVP – Nevirapine EFV – Efavirenz LPV/r – Ritonavir-boosted lopinavir AZT – Zidovudine TDF – Tenofovir ABC – Abacavir DNV/r – Ritonavir-boosted darunavir