Figure 7. Memory cell frequencies are similar in wt and Sca1KO mice.
T cell memory in Sca1KO and wt mice was quantified by ICCS 50–60 days after infection. Panel A. Epitope-specific CD8+ T cells; and panel B, epitope-specific CD4+ T cells. In each panel, the numbers within the left set of dot plots identify the epitope-specific IFNγ+ T cells, and the numbers in the right set of dot plots identify memory IL-2+ T cells. The numbers represent the fraction of cytokine-producing cells as a percentage of all spleen cells. Data are representative of 6 mice per group, analyzed in 3 independent experiments.