Table-I.
Virus-specific cellular response in macaques immunized with Vac-IIa or Vac-III and challenged with cocktail virus
| Macaque | Virus-specific T cells/106 PBMC on weeks post-challenge |
||||||
|---|---|---|---|---|---|---|---|
| 0 | 1 | 3 | 8 | 12 | 16 | 21 | |
| Vac-II | |||||||
| RGq5 | 0 | 10 | 235 | 530 | 760 | 1070 | 295 |
| RHt5 | 0 | 220 | 20 | 30 | 110 | 75 | 0 |
| RHu5 | 0 | 25 | 125 | 130 | 145 | 280 | 15 |
| RIs5 | 0 | 15 | 125 | 35 | 5b | ||
| Vacc-III | |||||||
| RKq5 | 0 | 385 | 135 | 230 | 100 | 110 | 25 |
| RMt5 | 0 | 35 | 425 | 85 | 160 | 415 | 540 |
| ROq5 | 0 | 45 | 225 | 70 | 45 | 240 | 170 |
| RPn5 | 0 | 70 | 485 | 350 | 205 | 325 | 215 |
a
The ELISPOT results are presented as number of virus-specific cells/million PBMC
b
The animal was euthanized at week 14, post-challenge