Table-II.
Viral DNA distribution in plasma, lung, spleen and 3 brain regions of macaques immunized with Vac-III and challenged with pathogenic SHIVs and SIV
| Macaque RKq5 | Challenge vpu | Vaccine vpu | KU2 env | 89.6 env | SIV 17E env |
|---|---|---|---|---|---|
| Virus in plasma | not done | not done | + | + | + |
| Lung | + | - | + | + | + |
| Spleen | + | - | - | + | + |
| Lymph Node | + | - | + | + | + |
| Occipetal Cortex | - | - | - | - | - |
| Parietal Cortex | + | + | - | - | - |
| Basal Ganglia | + | + | - | - | - |
| Macaque RMt5 | Challenge vpu | Vaccine vpu | KU2 env | 89.6 env | SIV 17E env |
| Virus in plasma | not done | not done | - | + | + |
| Lung | + | - | - | - | - |
| Liver | + | - | + | - | + |
| Spleen | + | - | + | + | + |
| Lymph Node | + | - | - | + | + |
| Occipetal Cortex | - | - | - | - | - |
| Parietal Cortex | - | - | - | - | - |
| Basal Ganglia | - | - | - | - | + |