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Intrinsic dissociation constants of SNAT2 transporters for alanine and Na+
The ranges of KAA and KNa given for SNAT2T384A all resulted in similar deviations of the theoretical data from the experimental data set, as determined by a least squares minimization approach using Equations 1 and 2.
| SNAT2WT | SNAT2T384A | |
|---|---|---|
| KAA (μm), alanine | 140 | 80–120 |
| KNa (mm) | 115 | 15,000–20,000 |
