Table 2.
Variable | Number (range or percent) or median (range) (n = 41) |
---|---|
Age at second auto-SCT | 54 years (28–73) |
Cytogenetics | |
Any result | 25 (61%) |
Abnormal result | 9 (22%) |
Time from first to second auto-SCT | 37 months (3–91) |
Number of prior lines of therapy | 3 (1–10) |
Specific therapies prior to second auto-SCT | |
Prior thalidomide | 19 (46%) |
Prior lenalidomide | 9 (22%) |
Prior bortezomib | 24 (59%) |
Responding disease prior to auto-SCT | 15 (37%) |
Conditioning | |
Melphalan 200 mg/m2 | 12 (29%) |
Reduced dose melphalan | 11 (27%) |
Melphalan/TBI | 14 (34%) |
BU/CY | 3 (7%) |
CY/TBI | 1 (2%) |
Response | |
CR | 2 (5%) |
VGPR | 4 (10%) |
PR | 15 (37%) |
SD | 11 (27%) |
PD | 6 (15%) |
Could not be assessed | 3 (7%) |
Treatment-related mortality | 3 (7%) |
Abbreviations: PD = progressive disease; PR = partial response; SD = stable disease; VGPR = very good partial response.