Table 3.
3A. Any flushing in the past 4 weeks | ||||
---|---|---|---|---|
Atorvastatin/Niacin (n=19) |
Niacin/Atorvastatin (n=17) |
|||
Study Visit: | Niacin Dose | Yes | Niacin Dose | Yes |
4 | 0 | - | 500 | 29 |
5 | 0 | - | 1000 | 59 |
6 | 0 | - | 1500 | 47 |
7 | 500 | 47 | 1500 | 41 |
8 | 1000 | 47 | 1500 | 59 |
9 | 1500 | 68 | 1500 | 41 |
3B. Most frequent level of flushing | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Severity: | 1 | 2 | 3 | 4 | 5 | 6 | 1 | 2 | 3 | 4 | 5 | 6 |
Study Visit: | ||||||||||||
4 | - | - | - | - | - | - | 0 | 18 | 0 | 6 | 6 | 0 |
5 | - | - | - | - | - | - | 6 | 6 | 18 | 12 | 12 | 6 |
6 | - | - | - | - | - | - | 0 | 12 | 6 | 18 | 12 | 0 |
7 | 5 | 16 | 5 | 5 | 16 | 0 | 6 | 18 | 6 | 12 | 0 | 0 |
8 | 0 | 5 | 16 | 21 | 5 | 0 | 6 | 29 | 6 | 12 | 6 | 0 |
9 | 5 | 11 | 21 | 11 | 21 | 0 | 12 | 24 | 6 | 0 | 0 | 0 |
3C. Strongest flushing feeling | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Severity: | 1 | 2 | 3 | 4 | 5 | 6 | 1 | 2 | 3 | 4 | 5 | 6 |
Study Visit: | ||||||||||||
4 | - | - | - | - | - | - | 0 | 6 | 12 | 0 | 12 | 0 |
5 | - | - | - | - | - | - | 0 | 6 | 12 | 18 | 6 | 0 |
6 | - | - | - | - | - | - | 0 | 12 | 0 | 12 | 18 | 6 |
7 | 5 | 5 | 0 | 11 | 26 | 0 | 0 | 18 | 6 | 6 | 12 | 0 |
8 | 0 | 5 | 11 | 21 | 11 | 0 | 0 | 29 | 0 | 12 | 24 | 0 |
9 | 5 | 11 | 11 | 16 | 21 | 5 | 6 | 18 | 6 | 12 | 0 | 0 |
3D. Actions related to flushing | ||||||||
---|---|---|---|---|---|---|---|---|
Action: | Consider Decrease | Decrease | Took ASA | ASA Helped | Consider Decrease | Decrease | Took ASA | ASA Helped |
Study Visit: | ||||||||
4 | - | - | - | - | 0 | 0 | 6 | 6 |
5 | - | - | - | - | 0 | 0 | 18 | 18 |
6 | - | - | - | - | 18 | 0 | 24 | 24 |
7 | 0 | 0 | 5 | 5 | 0 | 0 | 18 | 18 |
8 | 11 | 5 | 11 | 11 | 0 | 0 | 29 | 18 |
9 | 11 | 0 | 21 | 16 | 0 | 0 | 18 | 18 |
Severity:
1 – Tingle
2 – Warm, few minutes
3 – Warm, red, 15 minutes
4 – Warm, red, 30 minutes
5 – Hot, flushed, 31–60 minutes
6 – Intense, > 60 minutes