Table IV.

Haplotype blocks in the 5q31-33 region and associations with symptomatic S. japonicum infection

Block	Haplotype	Case, Control Ratios	X2 value	p-value
Block 1
GTCTT	0.389	81.0 : 141.0, 105.0 : 151.0	1.028	0.3105
GCATT	0.226	49.0 : 173.0, 59.0 : 197.0	0.065	0.7983
TCATC	0.159	48.0 : 174.0, 28.0 : 228.0	10.15	0.0014*
GCCCT	0.157	25.0 : 197.0, 50.1 : 205.9	6.208	0.0127
GCCTT	0.065	17.0 : 205.0, 13.9 : 242.1	0.986	0.3206
Block 2
AA	0.533	121.4 : 100.6, 133.1 : 122.9	0.345	0.5569
GA	0.232	44.1 : 177.9, 66.9 : 189.1	2.62	0.1055
GG	0.23	54.2 : 167.8, 55.8 : 200.2	0.469	0.4933
Block 3
TG	0.645	141.0 : 81.0, 167.5 : 88.5	0.193	0.6603
CG	0.198	50.0 : 172.0, 44.5 : 211.5	1.99	0.1583
CA	0.157	31.0 : 191.0, 44.0 : 212.0	0.934	0.3338
Block 4
AC	0.763	162.0 : 60.0, 202.9 : 53.1	2.608	0.1063
CT	0.174	45.0 : 177.0, 38.0 : 218.0	2.44	0.1183
CC	0.063	15.0 : 207.0, 15.1 : 240.9	0.152	0.6968
Block 5
GG	0.652	147.0 : 75.0, 164.7 : 91.3	0.182	0.6694
AG	0.231	44.0 : 178.0, 66.3 : 189.7	2.463	0.1165
AA	0.117	31.0 : 191.0, 25.0 : 231.0	2.026	0.1546
Block 6
TTTA	0.795	172.0 : 50.0, 208.0 : 48.0	1.037	0.3085
CCGG	0.145	33.7 : 188.3, 35.7 : 220.3	0.149	0.6996
CCTG	0.049	13.3 : 208.7, 10.2 : 245.8	0.985	0.321

^*Still significant after permutation test at a p<0.05 level