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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Int J Cancer. 2009 Jun 1;124(11):2621–2633. doi: 10.1002/ijc.24249

Table 2.

Identities of proteins found in exosomes

Ion transport
 UniRef100_Q3TIC2 Ras homolog gene family, member B

 UniRef100_Q8K314 ATPase, Ca++ transporting, plasma membrane 1

 UniRef100_P14824 Annexin A6

 UniRef100_Q3UMR9 Solute carrier family 5 (inositol transporters), member 3

 UniRef100_P09528 Ferritin heavy chain 1

 UniRef100_P49817 Caveolin, caveolae protein 1

 UniRef100_Q8VDN2 ATPase, Na+/K+ transporting, alpha 1 polypeptide

 UniRef100_Q3TIP8 Chloride intracellular channel 1

 UniRef100_P97370 ATPase, Na+/K+ transporting, beta 3 polypeptide

 UniRef100_Q8CFE6 Solute carrier family 38, member 2

 UniRef100_A2ALM4 Solute carrier family 6 (neurotransmitter transporter, creatine), member 8

 UniRef100_P53986 Solute carrier family 16 (monocarboxylic acid transporters), member 1

 UniRef100_P46467 Vacuolar protein sorting 4b (yeast
Apoptosis
 UniRef100_Q8BH78 Reticulon 4

 UniRef100_Q3TIC2 Ras homolog gene family, member B

 UniRef100_P12815 Programmed cell death 6

 UniRef100_P49769 Presenilin 1

 UniRef100_P26231 Catenin (cadherin associated protein), alpha 1

 UniRef100_P62960 Y box protein 1

 UniRef100_P68510 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

 UniRef100_Q3U2W7 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

 UniRef100_A1E2B8 Heat shock protein 1A

 UniRef100_P10126 Eukaryotic translation elongation factor 1 alpha 1

 UniRef100_Q3TED2 Programmed cell death 6 interacting protein
Endocytosis
 UniRef100_Q62351 Transferrin receptor

 UniRef100_Q8BH64 EH-domain containing 2

 UniRef100_Q3TLP8 RAS-related C3 botulinum substrate 1

 UniRef100_Q91ZX7 Low density lipoprotein receptor-related protein 1

 UniRef100_P49817 Caveolin, caveolae protein 1

 UniRef100_P35278 RAB5C, member RAS oncogene family
Protein transport
 UniRef100_Q3TIC2 Ras homolog gene family, member B

 UniRef100_P49769 Presenilin 1

 UniRef100_Q14AA6 RIKEN cDNA 1700009N14 gene

UniRef100_P68510 Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

 UniRef100_Q5SXR6 Clathrin, heavy polypeptide (Hc)

 UniRef100_Q3UK08 Tumor susceptibility gene 101

 UniRef100_Q3UUX9 guanosine diphosphate (GDP) dissociation inhibitor 2

 UniRef100_Q3TED2 programmed cell death 6 interacting protein

 UniRef100_P35278 RAB5C, member RAS oncogene family

 UniRef100_O09044 synaptosomal-associated protein 23

 UniRef100_P61028 RAB8B, member RAS oncogene family

 UniRef100_P53994 RAB2A, member RAS oncogene family

 UniRef100_P46467 vacuolar protein sorting 4b (yeast)

 UniRef100_Q8R0J7 vacuolar protein sorting 37B (yeast)

 UniRef100_Q8R105 vacuolar protein sorting 37C (yeast)

 UniRef100_Q9D1C8 vacuolar protein sorting 28 (yeast)

 UniRef100_Q8BHH2 RAB9B, member RAS oncogene family

 UniRef100_P55258 RAB8A, member RAS oncogene family

 UniRef100_P46638 RAB11B, member RAS oncogene family

 UniRef100_Q50HW9 RAB14, member RAS oncogene family
Metabolic process
 UniRef100_Q3TED3 ATP citrate lyase

 UniRef100_P49769 presenilin 1

 UniRef100_P06151 lactate dehydrogenase A

 UniRef100_P14152 malate dehydrogenase 1, NAD (soluble)

 UniRef100_P10852 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

 UniRef100_Q14AA6 RIKEN cDNA 1700009N14 gene

 UniRef100_P19096 fatty acid synthase

 UniRef100_P17751 triosephosphate isomerase 1

 UniRef100_Q05816 fatty acid binding protein 5, epidermal

 UniRef100_A6ZI47 aldolase 1, A isoform, retrogene 2

 UniRef100_Q9DBJ1 phosphoglycerate mutase 1

 UniRef100_P15532 similar to Nucleoside diphosphate kinase A (NDK A)

 UniRef100_Q01768 non-metastatic cells 2, protein (NM23B) expressed in

 UniRef100_Q3UMR9 solute carrier family 5 (inositol transporters), member 3

 UniRef100_P68510 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

 UniRef100_P59108 copine II

 UniRef100_Q61753 3-phosphoglycerate dehydrogenase

 UniRef100_P49817 caveolin, caveolae protein 1

 UniRef100_P58242 sphingomyelin phosphodiesterase, acid-like 3B

 UniRef100_Q3TXD3 vesicle amine transport protein 1 homolog (T californica)

 UniRef100_P62774 myotrophin

 UniRef100_P50247 S-adenosylhomocysteine hydrolase

 UniRef100_P80316 chaperonin subunit 5 (epsilon)

 UniRef100_P42932 chaperonin subunit 8 (theta)

 UniRef100_P80317 chaperonin subunit 6a (zeta)

 UniRef100_P08030 adenine phosphoribosyl transferase

 UniRef100_Q3UK08 tumor susceptibility gene 101

 UniRef100_Q8VDN2 ATPase, Na+/K+ transporting, alpha 1 polypeptide

 UniRef100_A2A607 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Immune
 UniRef100_O19476 histocompatibility 2, D region locus 1

 UniRef100_P49769 presenilin 1

UniRef100_P04202 Transforming growth factor beta-1
Cell adhesion
 UniRef100_A2AKI5 integrin alpha V

 UniRef100_Q3TIC2 ras homolog gene family, member B

 UniRef100_P49769 presenilin 1

 UniRef100_Q3UNG0 laminin, gamma 1

 UniRef100_Q3UEG9 flotillin 2

 UniRef100_P10493 nidogen 1

 UniRef100_A2AU04 integrin alpha 6

 UniRef100_P02469 laminin B1 subunit 1

 UniRef100_O88792 F11 receptor

 UniRef100_P26231 catenin (cadherin associated protein), alpha 1

 UniRef100_Q64727 vinculin

 UniRef100_Q05793 perlecan (heparan sulfate proteoglycan 2)

 UniRef100_P40240 CD9 antigen

 UniRef100_P11688 integrin alpha 5 (fibronectin receptor alpha)

 UniRef100_Q3TLP8 RAS-related C3 botulinum substrate 1

 UniRef100_P09055 integrin beta 1 (fibronectin receptor beta)

 UniRef100_Q01768 non-metastatic cells 2, protein (NM23B) expressed in

 UniRef100_P16045 lectin, galactose binding, soluble 1

 UniRef100_P35441 thrombospondin 1

 UniRef100_Q3UHT9 myosin, heavy polypeptide 9, non-muscle

 UniRef100_P21956 milk fat globule-EGF factor 8 protein

 UniRef100_A2APM1 CD44 antigen

 UniRef100_ A2ABW7 laminin, alpha 5
Signal transduction
 UniRef100_Q3TIC2 ras homolog gene family, member B

 UniRef100_P10107 annexin A1

 UniRef100_Q3U7U8 RAS-related protein-1a

 UniRef100_Q14AA6 RIKEN cDNA 1700009N14 gene

 UniRef100_Q3TLP8 RAS-related C3 botulinum substrate 1

 UniRef100_P68510 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

 UniRef100_P49817 caveolin, caveolae protein 1

 UniRef100_P68254 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide

 UniRef100_Q99PT1 Rho GDP dissociation inhibitor (GDI) alpha; Rho GDP dissociation inhibitor (GDI) alpha

 UniRef100_Q9DAS9 guanine nucleotide binding protein (G protein), gamma 12

 UniRef100_P08752 guanine nucleotide binding protein (G protein), alpha inhibiting 2

 UniRef100_Q3U1B1 guanine nucleotide binding protein (G protein), beta 1

 UniRef100_Q3TJH1 guanine nucleotide binding protein (G protein), alpha inhibiting 3

 UniRef100_A2A607 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus

 UniRef100_P21278 guanine nucleotide binding protein, alpha 11

 UniRef100_P10833 Harvey rat sarcoma oncogene, subgroup R

 UniRef100_Q3UUX9 guanosine diphosphate (GDP) dissociation inhibitor 2

 UniRef100_Q3U2W7 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

 UniRef100_Q6ZQK2 IQ motif containing GTPase activating protein 1

 UniRef100_Q8CCG5 v-ral simian leukemia viral oncogene homolog B (ras related)

 UniRef100_P63321 v-ral simian leukemia viral oncogene homolog A (ras related)

 UniRef100_Q3TED2 programmed cell death 6 interacting protein

 UniRef100_P35278 RAB5C, member RAS oncogene family

 UniRef100_P61028 RAB8B, member RAS oncogene family; RAB8B, member RAS oncogene family

 UniRef100_P53994 RAB2A, member RAS oncogene family

 UniRef100_Q8BHH2 RAB9B, member RAS oncogene family

 UniRef100_P55258 RAB8A, member RAS oncogene family

 UniRef100_P46638 RAB11B, member RAS oncogene family

 UniRef100_Q50HW9 RAB14, member RAS oncogene family
Vesicle-mediated transport
 UniRef100_Q5SXR6 clathrin, heavy polypeptide (Hc)

 UniRef100_P59108 copine II

 UniRef100_Q3UUX9 guanosine diphosphate (GDP) dissociation inhibitor 2

 UniRef100_O09044 synaptosomal-associated protein 23

 UniRef100_P53994 RAB2A, member RAS oncogene family

 UniRef100_P13020 gelsolin

 UniRef100_P63024 vesicle-associated membrane protein 3
Differentiation
 UniRef100_A2AKI5 integrin alpha V

 UniRef100_Q3TIC2 ras homolog gene family, member B

 UniRef100_P49769 presenilin 1

 UniRef100_O88792 F11 receptor

 UniRef100_P09055 integrin beta 1 (fibronectin receptor beta)

 UniRef100_P16045 lectin, galactose binding, soluble 1

 UniRef100_P49817 caveolin, caveolae protein 1

 UniRef100_Q3UHT9 myosin, heavy polypeptide 9, non-muscle

 UniRef100_P62774 myotrophin; myotrophin

 UniRef100_P53783 SRY-box containing gene 1

 UniRef100_P17742 peptidylprolyl isomerase A (cyclophilin A)

 UniRef100_A0PJ91 heat shock protein 90, alpha (cytosolic), class A member 1

 UniRef100_Q3UK08 tumor susceptibility gene 101

 UniRef100_A2A607 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus

 UniRef100_P46935 E3 ubiquitin-protein ligase NEDD4

 UniRef100_P21278 guanine nucleotide binding protein, alpha 11

 UniRef100_Q3U2W7 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

 UniRef100_Q5M9P3 ribosomal protein S19
Cell cycle
 UniRef100_Q3TIC2 Ras homolog gene family, member B

 UniRef100_P14069 S100 calcium binding protein A6 (calcyclin)

 UniRef100_Q3UKW2 Calmodulin 1

 UniRef100_P10107 Annexin A1

 UniRef100_Q3U7U8 RAS-related protein-1a

 UniRef100_P42208 Septin 2

 UniRef100_P27661 H2A histone family, member X

 UniRef100_Q14AA6 RIKEN cDNA 1700009N14 gene

 UniRef100_P09055 Integrin beta 1 (fibronectin receptor beta)

 UniRef100_Q3V4A1 Serine/threonine kinase 11

 UniRef100_P60122 RuvB-like protein 1

 UniRef100_Q3UK08 Tumor susceptibility gene 101

 UniRef100_Q3UXQ6 Ribosomal protein S4, X-linked