Table 6.

Classification rules for the proposed unified staging system for Lewy body disorders. Density scores are derived from the Third Dementia with Lewy Bodies Consortium conference. Scores refer to range of scores for all regions within a subdivision. The criteria for each stage are outlined in the columns and are dependent on the LTS density scores within the regions, ie. olfactory bulb, brainstem, limbic and neocortical. Scores given in the table are for any individual area within that region. For example, a subject would be scored as brainstem predominant if the highest brainstem area score range (1–2 or 3–4) was higher than the highest limbic score range (0–1 or 1–2, respectively). Additionally, to qualify as any stage less than neocortical, the highest neocortical area score would have to be 0 or 1. For olfactory bulb-only stage, all other regional scores must all be 0. Otherwise, the olfactory bulb score does not affect scoring for any other stage.

Regional Score (DLB III)	I. Olfactory Bulb-Only	IIa. Brainstem Predominant	IIb. Limbic Predominant	III. Brainstem/Limbic	IV. Neocortical
Olfactory Bulb	Score 1–4	Score 0–4	Score 0–4	Score 0–4	Score 0–4
Brainstem	Scores all 0	Either a or b a. Scores 1–2 b. Scores 3–4	Either a or b a. Scores 0 b. Scores 1–2	Either a or b a. Scores 1–2 b. Scores 3–4	Scores 0–4
Limbic	Scores all 0	Match a & b with above a. Scores 0 b. Scores 1–2	Match a & b with above a. Scores 1–2 b. Scores 3–4	Match a & b with above a. Scores 1–2 b. Scores 3–4	Scores 0–4
Neocortical	Scores all 0	Scores 0–1	Scores 0–1	Scores 0–1	Scores 2–4