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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Pain. 2009 Jul 2;10(10):1073–1077. doi: 10.1016/j.jpain.2009.04.005

Figure 1.

Figure 1

Reversal of stress-induced enhancement of epinephrine hyperalgesia (28 d post stress, filled squares) by adrenal medullectomy (28 d post-stress, AMedX, filled triangles)) and reconstitution of the enhanced hyperalgesia (28 d post-stress, AMedX, + Epi, filled inverted triangles) by implants of epinephrine in A) the skin (dorsal aspect of the hind paw) and B) skeletal (gastrocnemius) muscle of the rat. Adrenal medullectomy, with or without epinephrine implants, was performed 14 days after the last sound stress exposure and rats were used for experiments 14 days after surgery.