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. Author manuscript; available in PMC: 2010 Oct 15.
Published in final edited form as: Biol Psychiatry. 2009 Jul 3;66(8):777–784. doi: 10.1016/j.biopsych.2009.05.019

Figure 5. TAN-67 activity is affected by disruption of DOR and MOR.

Figure 5

(A) TAN-67 (25 mg/kg) induced changes in ethanol consumption (A) or preference in wild-type, DOR (B) KO, MOR KO (C) and KOR KO (D) C57BL/6 mice (n=9). Thirty minutes after injection (vehicle or drug) ethanol and water consumption was measured over a 4 hour period. Percentage decrease is ((Basal-drug)/Basal)×100. Ethanol preference = ethanol consumption/(ethanol consumption + water consumption). (*p<0.05; **p<0.01; ***p<0.001; n.s., non significant).