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The TH inhibitor AMPT decreases dopamine and NADA levels in rat striata in a time-dependent fashion. (A) A time-dependent decrease in striatal levels of dopamine was observed when compared to control (time = 0) (** p < 0.01 at 90 min; *** p < 0.0005 at 180, 270, 360, and 450 min). (B) A time-dependent decrease in striatal levels of NADA was also observed when compared to control (time = 0) (* p < 0.05 at 270, 360, and 450 min) (n = 4 at each time point).
