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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Jul 10;1788(10):2259–2266. doi: 10.1016/j.bbamem.2009.06.022

Figure 5.

Figure 5

Tissue distribution analysis. (A) Liver sinusoidal uptake of cy3-siRNA in naked LPD (positive control) and PEGylated LPD. Nuclei (blue), F-actin (green), cy3-siRNA (red). Magnification = 1,600 x. Data are representative pictures from 3 mice in each group. (B) Fluorescence signal of FAM-labeled siRNA in different tissues detected by the Xenogen IVIS imaging system. Data are from two representative animals in each group. Data of the NCI-H460 model are reproduced from a previously published article with permission [7].