Figure 2.
Sample images to illustrate the treatment effect grading scale. For grade 1, effects were not apparent macroscopically (A - left), but at higher magnification (A - right), regions of cell disruption and necrosis were visible. For grade 0, no abnormal tissue was seen at low (B - left) or high (B - right) magnification. For grade 2, macroscopic regions of tissue fractionation or a void were seen, but the full target volume contained some viable tissue (C). For grade 3, the complete target volume was a void and/or necrotic. Note: dashed boxes represent approximate targeted volumes.