Table 1.
Frequencies of non-germline amino acid residues in B6.Sle1z-derived and B6-derived splenic B-cell repertoires
| Total number of clonally independent HCs | Frequency of mutations in HC1 | Frequency of mutations in HC CDR1 | Frequency of mutations in HC CDR2 | |
|---|---|---|---|---|
| B6 #1, total B-cell repertoire | 61 | 0.8% | 1.5% | 1.1% |
| B6 #2, total B-cell repertoire | 75 | 0.5% | 0.4% | 0.4% |
| B6.Sle1 #1, total B-cell repertoire | 76 | 0.9% | 0.6% | 1.5% |
| B6.Sle1 #2, total B-cell repertoire | 75 | 1.0% | 2.0% | 1.2% |
1
Indicated are the frequencies of amino-acid residues that are non-germline, when compared to the NCBI/IgBlast database.