Table 1.
Clinical descriptors, noninvasive DF parameters, invasive DF parameters, and kinematic DF parameters for all age groups.
| Age group | 30–40 | 41–45 | 46–50 | 51–55 | 56–60 | 61–65 | 66–70 | >70 | Average of all patients |
|---|---|---|---|---|---|---|---|---|---|
| Parameters | |||||||||
| Clinical Discriptors for all age groups | |||||||||
| N | 6 | 9 | 9 | 16 | 10 | 9 | 8 | 5 | 9±3 |
| Average age | 35 | 43 | 49 | 53 | 57 | 62 | 68 | 75 | 55±11 |
| Gender (m/f) | 3/3 | 8/1 | 5/4 | 9/7 | 7/3 | 6/3 | 4/4 | 3/2 | 45/27 |
| HR (bpm) | 75±17 | 68±8 | 72±10 | 67±8 | 64±10 | 69±14 | 66±12 | 68±8 | 68±11 |
| LVEF (%)* | 72±7 | 69±10 | 75±7 | 76±8 | 70±11 | 70±12 | 78±8 | 75±6 | 73±9 |
| LVEDV (ml) | 183±41 | 171±40 | 129±28 | 156±52 | 184±40 | 164±33 | 182±37 | 130±17 | 163±42 |
| LV mass (g) | 140±12 | 152±23 | 171±41 | 161±47 | 164±35 | 131±55 | 144±19 | 151±24 | 153±37 |
| Noninvasive DF parameters in all age groups | |||||||||
| E/A | 1.5±0.3 | 1.2±0.2 | 1.1±0.2 | 1.2±0.2 | 1.1±0.2 | 1.0±0.2 | 1.0±0.2 | 1.0±0.3 | 1.1±0.2 |
| VTIE/VTIA | 2.6±0.7 | 1.8±0.3 | 1.8±0.4 | 1.8±0.4 | 1.7±0.3 | 1.6±0.2 | 1.6±0.2 | 1.4±0.2 | 1.8±0.4 |
| DT (ms) | 176±23 | 190±27 | 183±26 | 213±40 | 217±46 | 214± 25 | 231±30 | 205±40 | 205±36 |
| Epeak (cm/s) | 0.9±0.1 | 0.7±0.1 | 0.8±0.1 | 0.8±0.2 | 0.7±0.1 | 0.8±0.2 | 0.8±0.1 | 0.8±0.2 | 0.8±0.2 |
| Apeak (cm/s) | 0.6±0.1 | 0.6±0.1 | 0.7±0.1 | 0.7±0.1 | 0.7±0.1 | 0.8±0.1 | 0.8±0.2 | 0.8±0.1 | 0.7±0.1 |
| E/E′ | 4.5±0.4 | 4.1±1.3 | 4.5±1.6 | 4.7±1.3 | 5.2±2.8 | 4.0±1.1 | 3.8±1.8 | 5.7±2.2 | 4.5±1.7 |
| AFF** (%) | 29±6 | 37±3 | 37±6 | 37±4 | 37±3 | 38±4 | 38±3 | 42±4 | 37±5 |
| IVRT (ms) | 64±10 | 62±14 | 68±17 | 76±14 | 81±12 | 72±18 | 79±12 | 80±13 | 73±15 |
| Invasive DF parameters in all age groups | |||||||||
| LVEDP (mmHg) | 17±4 | 15±3 | 16±6 | 16±4 | 18±4 | 17±2 | 16±5 | 18±3 | 17±4 |
| τ (ms) | 42±8 | 44±9 | 45±8 | 46±6 | 54±13 | 44±7 | 43±5 | 45±8 | 46±9 |
| +dP/dtmax(mmHg/s)(103) | 1.0±0.0 | 1.2±0.3 | 1.2±0.3 | 1.3±0.2 | 1.2±0.1 | 1.3±0.3 | 1.5±0.4 | 1.4±0.2 | 1.3±0.3 |
| −dP/dtmax (mmHg/s)(103) | −1.4±0.2 | −1.6±0.4 | −1.5±0.2 | −1.6±0.3 | −1.4±0.2 | −1.6±0.3 | −1.8±0.2 | −1.7±0.3 | −1.6±0.3 |
| Kinematic DF parameters in all age groups | |||||||||
| Oscillation ratio | 0.67 | 0.7 | 0.44 | 0.44 | 0.5 | 0.11 | 0.13 | 0.2 | 0.5 |
| c (1/s) | 13.7±2.3 | 16.6±2.7 | 18.7±5.6 | 19.7±5.1 | 19.7±4.7 | 18.3±3.5 | 21.8±3.9 | 25.7±4.0 | 19.2±4.9 |
| k (1/s+) | 210±43 | 208±39 | 203±43 | 206±59 | 174±56 | 182±36 | 181±34 | 226±61 | 197±48 |
| 1/2kxo2 (cm2/s2) | 0.9±0.2 | 0.8±0.3 | 1.1±0.4 | 1.3±0.8 | 1.3±0.4 | 1.2±0.5 | 1.4±0.5 | 1.6±0.8 | 1.2±0.6 |
| EVTI/(1/2kxo2) (s2/cm) | 0.13±0.02 | 0.14±0.05 | 0.11±0.03 | 0.12±0.06 | 0.09±0.02 | 0.12±0.04 | 0.09±0.03 | 0.08±0.02 | 0.11±0.04 |
| kxo (cm/s2) | 19.1±2.2 | 17.7±3.6 | 19.8±3.1 | 21.5±7.8 | 20.2±3.3 | 20.1±6.0 | 22.3±4.0 | 27.7±9.3 | 20.8±5.8 |
| KFEI | 0.61±0.06 | 0.56±0.04 | 0.55±0.03 | 0.54±0.02 | 0.52±0.01 | 0.54±0.02 | 0.52±0.01 | 0.51±0.01 | 0.54±0.04 |
*
LVEF determined by ventriculography
**
AFF, atrial filling fraction. LVEDV = Left ventricular end-diastolic volume from ventriculography. Data are presented as mean ± (SD)