Fig. 2.

Comparison of the aftD locus within Corynebacterianeae (A) and topology of AftD (B). Mtb, Mycobacterium tuberculosis; Msm, M. smegmatis; Nfc, Nocardia farcinica; Rho, Rhodococcus sp. RHA1_1; Cgl, Corynebacterium glutamicum ATCC 13032. The genomic regions flanking aftD are not well conserved among mycobacteria and other Corynebacterianeae (orthologous genes are highlighted accordingly). AftD is a hydrophobic protein predicted to span the membrane nine times. The hatched circle indicates the position of the predicted GT-C motif of the enzyme (DE-X₁₉-PP) (Berg et al. 2007).