Table 1.
Molecular results and characteristics of patients with hepatocellular carcinoma
| Patient | Etiology | Non-tumor tissue | Tumor tissue | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Fibrosis score (Ishak et al. 1995) | Methylight analysis | Immunohistochemistry | Differentiation (MacSween et al. 2002) | AFP (ng/ml) | Tumor size (in mm) | Metastasis | Methylight analysis | Immunohistochemistry | ||||||
| Result | PMR (%) | N15 | C20 | Result | PMR (%) | N15 | C20 | |||||||
| Hepatocellular carcinoma (HCC) | ||||||||||||||
| Case number | ||||||||||||||
| HCC1 | Alcoholic | 6 | Positive | 15.7 | 5 | 5 | Poorly | 709 | 140 | Intrahepatic | Positive | 62.94 | 3 | 5 |
| HCC2 | Cryptogenic | 2 | Positive | 24.95 | 5 | 6 | Moderately | <7.0 | 65 | No | Positive | 25.17 | 2 | 5 |
| HCC3 | Hemochromatosis | 4 | Positive | 12.36 | 5 | 5 | Moderately | <7.0 | 70 | Intrahepatic | Positive | 23.51 | 2 | 4 |
| HCC4 | Alcoholic | 3 | Positive | 11.63 | 5 | 5 | Poorly | 7.6 | 170 | Peritoneal | Positive | 28.97 | 3 | 4 |
| Carcinosis | ||||||||||||||
| HCC5 | Alcoholic | 4 | Positive | 21.47 | 5 | 5 | Poorly | 28,235 | 26 | No | Positive | 100 | 2 | 4 |
| HCC6 | Cryptogenic | 6 | Negative | 1.76 | 5 | 5 | Poorly | 14,558 | 40 | No | Positive | 77.37 | 3 | 4 |
| HCC7 | Cryptogenic | 2 | Positive | 13.91 | 3 | 4 | Poorly | 53,462 | 190 | No | Positive | 40.87 | 0 | 0 |
| HCC8 | Alcoholic | 6 | Positive | 39.92 | 5 | 5 | Moderately | <7.0 | 25 | No | Positive | 47.83 | 4 | 4 |
| HCC9 | Cryptogenic | 2 | Positive | 27.82 | 5 | 4 | Poorly | 213 | 120 | No | Positive | 52.46 | 5 | 4 |
| HCC10 | Alcoholic | 6 | Positive | 8.45 | 4 | 5 | Moderately | 27.4 | 55 | No | Positive | 100 | 3 | 4 |
| HCC11 | Alcoholic | 2 | Positive | 8.45 | 2 | 4 | Well | <7.0 | 22 | No | Positive | 23.42 | 3 | 4 |
| HCC12 | Alcoholic | 4 | Positive | 15.73 | 4 | 5 | Moderately | 10.4 | 50 | Lymph nodes | Positive | 32.61 | 2 | 3 |
| HCC13 | Cryptogenic | 5 | Positive | 6.4 | nd | nd | Moderately | <7.0 | 60 | No | Positive | 57.58 | nd | nd |
| HCC14 | Cryptogenic | 4 | Positive | 25.25 | nd | nd | Moderately | <7.0 | 55 | No | Positive | 62.63 | nd | nd |
| HCC15 | Alcoholic | 6 | Negative | 0 | nd | nd | Moderately | <7.0 | 24 | No | Positive | 100 | nd | nd |
| HCC16 | Cryptogenic | 2 | Negative | 0 | nd | nd | Moderately | 95,468 | 90 | No | Positive | 51.63 | nd | nd |
| HCC17 | Cryptogenic | 3 | Negative | 0 | nd | nd | Well | <7.0 | 90 | No | Positive | 82.41 | nd | nd |
| HCC18 | Cryptogenic | 2 | Positive | 13.25 | nd | nd | Moderately | 13.9 | 140 | No | Positive | 100 | nd | nd |
| HCC19 | Cryptogenic | 2 | Positive | 9.95 | nd | nd | Well | <7.0 | 120 | No | Positive | 62.1 | nd | nd |
nd not done, AFP alpha fetoprotein