Fig. 1.

Pedigree structure of family B008 and haplotype reconstruction at locus 19p13. The haplotypes correspond to microsatellite loci described in Table 1. The alleles written in bold were inferred, 0 marks unavailable alleles, x sites of recombination. Haplotypes shared by all affected patients and not present in unaffected are marked by the box. The DNA from individual “2” was not available