TABLE I.
Parameter | No Transfusion/ No CS (N=61) |
CS only (N=17) |
Transfusion only (N=29) |
Transfusion/CS (N=22) |
---|---|---|---|---|
Age (years) | 13 ± 6 | 11 ± 4 | 14 ± 5 | 10 ± 4* |
Prior ACS # | 3.3 ± 4.0 | 2.7 ± 2.0 | 4.8 ± 3.3 | 6.4 ± 4.9$ |
Prior HTN | 7% | 12% | 10% | 27% |
Asthma | 22% | 25% | 25% | 55%† |
HbF % | 7.9 ± 6.8 | 8.8 ± 7.2 | 4.1 ± 4.1† | 5.3 ± 5.1 |
Hydroxyurea | 11% | 19% | 48%‡ | 18%* |
P < 0.05 compared transfusion only
P < 0.01 compared to no transfusion/no CS and P < 0.05 compared to CS
P < 0.05 compared to no transfusion/no CS
P < 0.001 compared to no transfusion/no CS; CS indicates corticosteroids; ACS, acute chest syndrome; HTN, hypertension; HbF, fetal hemoglobin.