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Protocol of a definitive 5-fluorouracil (5-FU)/ cisplatin (CDDP) or nedaplatin (NDP)-based chemoradiotherapy. One course of treatment consisted of protracted venous infusions of 5-FU (400 mg/m2/day for days 1-5 and 8-12) and CDDP (or NDP) (40 mg/m2/day on days 1 and 8), and radiation (2 Gy/day on days 1-5, 8-12, and 15-19), with a second course (days 36-56) was repeated after a 2-week interval.
