Figure 9.

Taste aversion test in the control of body weight by ZC treatment. In (A), 15-month-old S-D rats weighing 650–850 g (n= 12) were given drinking water containing 2 g·L⁻¹ Equal Sweetener, with either no additives (DW) or ZC (3-mg CHP plus 10 mg zinc·L⁻¹) for 15 days. ZC still induced weight loss in the S-D rats in the presence of the artificial sweetener. In (B), 6-month-old C57BL/6J mice (n= 14) were divided into two groups of seven mice and treated with drinking water containing 32% sucrose (w/w), with either no additives (32% sucrose) or ZC (3-mg CHP plus 10 mg zinc·L⁻¹) for 15 days. The body weight gain in the group of mice treated with ZC was less than that in the controls (32% sucrose only). ***P < 0.001; **P < 0.01 (t-test).