Figure 3.

Effect of different inhibitors on vasodilatation evoked by 2-nitrooxyethylammoniumnitrate (AEN) in wild-type mice. AEN potency was determined after pre-incubation of isolated aortic ring segments for 30 min with (A) NS2028 (3 µM), PTIO (10 µM) or miconazol (25 µM) and (B) benomyl (10 µM), L-NAME (200 µM) or allopurinol (100 µM). Data are mean ± SEM of 6–12 independent experiments with tissue from different mice. *P < 0.05 versus control without treatment.