Table I.
Mean reciprocal titers of serum neutralizing (SN) antibody to types 1 and 2 Bovine viral diarrhea virus (BVDV) in heifers before and after vaccination (on day 0) with a modified-live virus vaccine or a placebo, breeding (on day 28), and intranasal challenge with a noncytopathic field isolate of BVDV (on day 205)
| BVDV field isolate type and heifer group | BVDV type to which SN antibody was demonstrated; titer on various days of the study |
|||||||
|---|---|---|---|---|---|---|---|---|
| Type 1 |
Type 2 |
|||||||
| 0 | 28 | 205 | 219 | 0 | 28 | 205 | 219 | |
| Type 1 | ||||||||
| Vaccinated (n = 25) | 0 | 1877 | 1058 | 4403 | 0 | 90 | 89 | 282 |
| Control (n = 12) | 0 | 0 | 0 | 17 | 0 | 0 | 0 | 5 |
| Type 2 | ||||||||
| Vaccinated (n = 28) | 0 | 1910 | 985 | 3835 | 0 | 27 | 67 | 746 |
| Control (n = 18) | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 16 |