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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Cancer Res. 2009 Sep 29;69(19):7826–7834. doi: 10.1158/0008-5472.CAN-09-1564

Figure 3. Pleiotropic effects of S100P silencing.

Figure 3

A, Expression levels of S100P-COR genes in HTG cell lines altered by S100P knock down. Red bars - CCdl54. Blue bars - CCdl675. Open bars - control siRNA. Solid bars - S100P siRNA. B, Reduction in the number of anti BrdU stained proliferating cells in 3 HTG cell lines transfected with S100P siRNA. Error bars indicate standard deviation between triplicate assays. C, Apolar morphology of HTG colonies propagated in matrigel (top); normalized by S100P silencing to resemble polarized acinar structures (bottom). Blue - immunolocalization of anti S100P, green – actin localization by phalloidin, and red - immunolocalization of anti integrin alpha6. D, Reduction in migration potential induced by S100P siRNA in HTG cell lines. Standard error bars represent triplicate assays.