TABLE 2.

Summary of structural information related to native β-pairings within the human TTR dimer structure (PDB: 1F41)

For each pairing between two β-strands the orientation parallel (p) or antiparallel (a), the weight θ_k of its contribution to the total stability score, the number of involved residue pairs n_k and the first and last residue pair are listed. Pairings 1–5 and 6–9 compose two separate β-sheets. Pairings 5 and 9 are established between different monomers.

Pairing	Orientation	θk	nk	First pair	Last pair
1	a	1	2	14–55	15–54
2	a	1	2	17–24	18–23
3	p	1	7	12–105	18–111
4	a	1	9	104–123	112–115
5	a	0.5	5	115–119	119–115
6	a	1	7	29–48	35–42
7	a	1	6	30–73	35–68
8	a	1	7	67–97	73–91
9	a	0.5	7	89–95	95–89