Binding affinity of human Ago2 for antisense RNA containing 2′-methoxyethyl substitutions
The dissociation constants (Kd) for human Ago2 containing the unmodified antisense RNA (0) and antisense RNA with 2′-methoxyethyl substitutions (underlined) were determined as described under “Materials and Methods.” The errors reported for the Ago2 binding affinities are based on three trials.