Table 3.

Comparison of sensitivity, specificity, PPV, and NPV of individual marker expression in all benign versus malignant thyroid lesions

Markers		Negative	Positive	Total	Combo values
Gal-3	Benign	34	10	44	Sensitivity	0.926
	Malignant	2	25	27	Specificity	0.773
					PPV	0.714
Total		36	35	71	NPV	0.944
Ret	Benign	30	14	44	Sensitivity	0.852
	Malignant	4	23	27	Specificity	0.682
					PPV	0.622
Total		34	37	71	NPV	0.882
HBME-1	Benign	32	12	44	Sensitivity	0.889
	Malignant	3	24	27	Specificity	0.727
					PPV	0.667
Total		35	36	71	NPV	0.914
CK19	Benign	31	13	44	Sensitivity	0.852
	Malignant	4	23	27	Specificity	0.705
					PPV	0.639
Total		35	36	71	NPV	0.886

Gal-3-Galectin-3; Ret-Ret oncoprotein; CK 19-Cytokeratin 19; PPV-Positive predictive value; NPV-Negative predictive value