Fig. 2.
Diagram of truncation and substitution mutants used in this study. Tac (gray box) was fused to the TM and TIR domains of TLR9 (amino acids 817–1032). Mutant names are indicated to the left. The numbering scheme is according to that used in Genbank, AF259262. Truncations were generated by introducing a stop codon (*) at the indicated amino acid.