Figure 1.
Top: Changes in blood pressure over time (n=3–4 animals per group)
Bottom: Renal blood flow (RBF, a), glomerular filtration rate (GFR, b), and cortical perfusion (c) at baseline and in responses to acetylcholine in normal, renal artery stenosis (RAS), and RAS treated with autologous endothelial progenitor cells (RAS+EPC) animals. EPC infusion did not decrease blood pressure in RAS. The blunted basal and challenged renal hemodynamics and function in RAS were normalized after EPC, suggesting restoration of renovascular endothelial function. *p<0.05 vs. Normal, †p<0.05 vs. baseline, ** p<0.05 vs. Normal (two-way repeated measures ANOVA)