Table 1.

Characteristics and basal stenotic kidney function (mean ± SEM) in normal, renal artery stenosis (RAS), and RAS pigs treated with autologous endothelial progenitor cells (RAS+EPC).

		Normal n=7	RAS n=7	RAS+EPC n=7
Body weight (kg)		47.3±2.3	50.7±1.9	51.7±2.0
Degree of stenosis (%)		0.0±0.0	70.4±5.2*	69.3±6.0*
Mean arterial pressure (mmHg)		104.7±2.2	140.2±7.1*	130.3±6.9*
Plasma renin activity (ng/mL/h)	IVC	0.22±0.04	0.19±0.03	0.21±0.04
	Stenotic kidney	-------	0.20±0.04	0.31±0.13
	Contralateral kidney	-------	0.19±0.02	0.17±0.06
Plasma ADMA (umol/L)		1.47±0.1	1.46±0.08	1.57±0.15
Renal volume (cc)	Cortex	98.6±7.1	47.0±13.4*	99.2±5.0
	Medulla	43.9±2.4	21.9±6.4*	20.5±2.5*
Renal blood flow (mL/min)		566.5±46.9	301.9.6±92.5*	452.93±24.7#
Glomerular filtration rate (mL/min)		70.8±4.3	47.9±10.1*	62.7±1.5
Perfusion (mL/min/cc)	Cortex	4.1±0.3	2.7±0.6	4.1±0.2
	Medulla	2.7±0.4	2.7±0.2	2.4±0.2
Proteinuria (ug/mL)		14.4±3.7	21.6±4.8	16.8±4.1

MAP: mean arterial pressure (measured during CT studies). IVC: inferior vena cava. ADMA: Asymmetric Dimethylarginine

^*p<0.05 vs. normal †p<0.05 vs. RAS.

^#p=0.06 vs. normal.