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M-LDH physically associated with Kir6.2/SUR2A is required for counteracting chemical hypoxia-induced decrease in intracellular ATP. Bar graphs showing luciferase luminescence in control cells and cells infected with gly193M-LDH/ΔM-LDH under control conditions (normoxia) and after treatment with 10 mM DNP (hypoxia). Each bar represents mean ± SEM (n = 5). *P < 0.05.
