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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Virus Res. 2009 Feb 4;141(1):71–80. doi: 10.1016/j.virusres.2008.12.018

Fig. 5.

Fig. 5

MAL2-11B inhibits the initiation of SV40 DNA synthesis. Increasing concentrations of MAL2-11B or an equal volume of DMSO were incubated with TAg, pol-prim, hRPA, and Top1, and the monopolymerase assay was performed as described in Section 2. The DNA products were resolved on an agarose gel. Lanes 1–3 contain increasing amounts of DMSO which correspond to the volume of MAL2-11B utilized in the reactions shown in lanes 4–6 (25 µM, 50 µM, and 100 µM, respectively). A control reaction performed in the absence of pol-prim is shown in lane 7, and size standards are indicated to the left of the figure.