Table 3.
Incremental Cost-Effectiveness Ratio for Questionnaire-%CDT Strategy Versus Questionnaire Only as a Function of Age, Use of Life Years, Patient Costs Inclusion, and Screening Effects
| Age | ICER ($/QALY) |
ICER ($/LY) |
ICER without patient costs included ($/QALY) |
ICER with screening effects included in intervention strategiesa |
|---|---|---|---|---|
| 25 | 3,380 | 18,200 | Dominatesb | Dominates |
| 50 | 15,500 | 58,600 | 5,030 | 2,290 |
| 75 | 243,000 | 441,000 | 164,000 | 128,000 |
ICER, incremental cost-effectiveness ratio; QALY, quality-adjusted life year; LY, life year.
a
Screening effect pertains to the transition from unhealthy to healthy state after positive screening but without formal intervention. In the base case, we applied this effect only to the No Screening strategy. In sensitivity analysis, we applied this to all strategies.
b
Dominates implies that the Questionnaire-%CDT strategy cost less and gained more QALYs compared with the Questionnaire Only strategy.